Coagulant and fibrinolytic activities of a metastasising and non-metastasising tumour line.
Indian J Cancer
;
1990 Jun; 27(2): 63-73
Artículo
en Inglés
| IMSEAR
| ID: sea-50545
ABSTRACT
The two types of transplantable methyl cholanthrene induced fibrosarcoma in rats was used to find out the possible relationship between the fibrinolytic, procoagulant activities and the metastasizing capacity of the tumours. The highly metastatic tumour seems to possess high fibrinolytic activity as compared to the low metastatic one. Interestingly enough, it was found that the procoagulant and fibrinolytic activities in the highly metastasising tumour bear inverse relationship with each other in relation to time of tumour growth. The procoagulant activity of the tumour bypasses factor VII and acts at factor X level. The plasminogen activator present in the tumour tissue has been characterized by sephadex G-200 column chromatography and PAGE.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Coagulación Sanguínea
/
Masculino
/
Células Tumorales Cultivadas
/
Fibrinólisis
/
Fibrosarcoma
/
Animales
/
Metilcolantreno
/
Metástasis de la Neoplasia
/
Trasplante de Neoplasias
Idioma:
Inglés
Revista:
Indian J Cancer
Año:
1990
Tipo del documento:
Artículo
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