Cytological study of copper in oral submucous fibrosis.
Artículo
en Inglés
| IMSEAR
| ID: sea-51870
ABSTRACT
BACKGROUND:
Habitual arecanut chewing is associated with Oral Submucous Fibrosis (OSF). High copper content in arecanut plays a vital role in pathogenesis of OSF. This study evaluates the copper-staining pattern of buccal epithelial cells in oral cytological smears of non-chewers, chewers, and OSF. MATERIALS &METHODS:
Alcohol fixed buccal epithelial smears of 10 histopathologically confirmed cases of OSF, 10 chewers without lesion, and 5 nonchewers were stained with modified Rhodamine technique and studied under the light microscope. Buccal epithelial smears of non-chewers dipped in copper sulphate solution were used as known positive for copper.RESULT:
Copper appeared as shades of palered within the cytoplasm of chewers and did not show any stain in non-chewers. Intense red stain was seen in OSF smears as dark granules within the cytoplasm.CONCLUSION:
Intense staining of copper in OSF buccal smears, than in the chewers supports the role of copper in the pathogenesis of OSF.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Fibrosis de la Submucosa Bucal
/
Areca
/
Rodaminas
/
Humanos
/
Cobre
/
Citoplasma
/
Células Epiteliales
/
Colorantes Fluorescentes
/
Mucosa Bucal
Idioma:
Inglés
Año:
2004
Tipo del documento:
Artículo
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