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High seroprevalence of HSV-1 and HSV-2 in STD clinic attendees and non-high risk controls: a case control study at a referral hospital in south India.
Indian J Dermatol Venereol Leprol ; 2005 Jan-Feb; 71(1): 26-30
Artículo en Inglés | IMSEAR | ID: sea-52494
ABSTRACT

BACKGROUND:

In Asia, HSV seroprevalence studies are sparse and they have recorded lower prevalence of HSV infection, especially HSV-2.

AIMS:

To ascertain the seroprevalence of HSV-1 and HSV-2 in patients attending a STD clinic in a referral hospital in south India and to compare it with a control group.

METHODS:

The study included 135 consecutive STD cases having history of ulcerative or non-ulcerative STD in the present or in the past 5 years and 135 age and sex-matched controls. Diagnostic serology was done for HSV-1 and HSV-2 using type specific IgG by indirect immunoassay using ELISA. The results were analyzed utilizing Chi- square test.

RESULTS:

Amongst 135 STD clinic cases, 106 cases were males and 29 cases were females with male to female ratio of 3.651. The mean age was 32.2 years (range 16-65 years). Among study group cases, 112 (82.9%) cases were co-infected with HSV-1 and HSV-2, 11 (8.1%) cases were seropositive for HSV-1 alone and 3 (2.2%) cases were seropositive for HSV-2 alone. In the control group, 112 (82.9%) cases were co-infected with HSV-1 and 2, 12 (9.6%) for HSV-1 alone and 1(0.8%) for HSV-2 alone. Correlation of HSV-1 and HSV-2 serology with various demographic and behavioral factors was statistically insignificant.

CONCLUSIONS:

Seroprevalence of HSV-1 and HSV-2 in STD clinic cases and control group is high, similar to that recorded in sub-Saharan Africa. Thus, serological studies for HSV-1 and HSV-2 cannot be taken as a marker of sexual behavior in our set of population.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Valores de Referencia / Derivación y Consulta / Anciano / Femenino / Humanos / Masculino / Herpes Genital / Enfermedades de Transmisión Sexual / Estudios de Casos y Controles / Estudios Seroepidemiológicos Tipo de estudio: Estudio de etiología / Estudio observacional / Estudio de prevalencia / Factores de riesgo País/Región como asunto: Asia Idioma: Inglés Revista: Indian J Dermatol Venereol Leprol Año: 2005 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Valores de Referencia / Derivación y Consulta / Anciano / Femenino / Humanos / Masculino / Herpes Genital / Enfermedades de Transmisión Sexual / Estudios de Casos y Controles / Estudios Seroepidemiológicos Tipo de estudio: Estudio de etiología / Estudio observacional / Estudio de prevalencia / Factores de riesgo País/Región como asunto: Asia Idioma: Inglés Revista: Indian J Dermatol Venereol Leprol Año: 2005 Tipo del documento: Artículo