Dexamethasone-cyclophosphamide pulse therapy in systemic lupus erythematosus.
Indian J Dermatol Venereol Leprol
;
2005 Jan-Feb; 71(1): 9-13
Artículo
en Inglés
| IMSEAR
| ID: sea-53074
ABSTRACT
BACKGROUND AND AIMS:
Therapy systemic lupus erythematosus (SLE) has been generally discouraging. Methyl-prednisolone pulse therapy has been used for various connective tissue disorders. We used intravenous dexamethasone cyclophosphamide pulse therapy to treat SLE.METHODS:
Fourteen patients (10 females and 4 males) between the age of 15-48 years with definite or classical clinical criteria laid by American Rheumatism Association criteria were treated by Dexamethasone-Cyclophosphamide pulse (DCP) therapy at our center.RESULTS:
It was possible to induce a complete clinical remission with DCP therapy in most of the patients thereby offering them life free from disease and drugs. The side effects commonly observed with conventional daily dose regimen of corticosteroids were not present or were mild.CONCLUSIONS:
Almost all patients had good response after 3-4 pulses to allow them a normal life style. Fever, malar rash and oral ulceration responded early but photosensitivity, discoid rash, alopecia and joint pains took some more time.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Índice de Severidad de la Enfermedad
/
Femenino
/
Humanos
/
Masculino
/
Dexametasona
/
Estudios Prospectivos
/
Estudios Retrospectivos
/
Estudios de Seguimiento
/
Adolescente
/
Resultado del Tratamiento
Tipo de estudio:
Estudio de etiología
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Indian J Dermatol Venereol Leprol
Año:
2005
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS