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In vitro activity of antimicrobial agents against oxacillin resistant staphylococci with special reference to Staphylococcus haemolyticus.
Indian J Med Microbiol ; 2007 Jan; 25(1): 50-2
Artículo en Inglés | IMSEAR | ID: sea-53427
ABSTRACT
One hundred and sixty seven isolates of staphylococci isolated from the inpatients of a tertiary care referral hospital in South India were speciated and activity of oxacillin, glycopeptides, linezolid and quinupristin/dalfopristin against these isolates was tested by broth microdilution method. Of the 114 coagulase negative staphylococci (CoNS), 49.1 % were S. haemolyticus, isolated predominantly from urine (64.6%), while the rest belonged to 11 other species. More than half the isolates of S. aureus (52.8%) and 68.4% of the CoNS were oxacillin resistant. All the strains were uniformly susceptible to vancomycin, linezolid and quinupristin/dalfopristin; but 25.6% isolates of S. haemolyticus showed reduced susceptibility to teicoplanin (MIC 8-16 mg/L). Our study demonstrates the high prevalence of oxacillin resistance among hospital isolates of S. aureus and CoNS in India. Vancomycin, along with the newer agents like linezolid and quinupristin/dalfopristin remains the drug of choice for treating multi drug resistant staphylococcal infections.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Oxacilina / Staphylococcus / Vancomicina / Pruebas de Sensibilidad Microbiana / Virginiamicina / Teicoplanina / Oxazolidinonas / Farmacorresistencia Bacteriana Múltiple / Staphylococcus haemolyticus / India País/Región como asunto: Asia Idioma: Inglés Revista: Indian J Med Microbiol Asunto de la revista: Microbiology Año: 2007 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Oxacilina / Staphylococcus / Vancomicina / Pruebas de Sensibilidad Microbiana / Virginiamicina / Teicoplanina / Oxazolidinonas / Farmacorresistencia Bacteriana Múltiple / Staphylococcus haemolyticus / India País/Región como asunto: Asia Idioma: Inglés Revista: Indian J Med Microbiol Asunto de la revista: Microbiology Año: 2007 Tipo del documento: Artículo