Risk factors and associated problems in the management of infections with methicillin resistant Staphylococcus aureus.
Indian J Med Microbiol
;
2006 Jul; 24(3): 182-5
Artículo
en Inglés
| IMSEAR
| ID: sea-53645
ABSTRACT
PURPOSE:
It is necessary to define the problem of methicillin resistant Staphylococcus aureus (MRSA) in every hospital to evolve control strategies. The objectives of this study were to determine factors influencing the persistence of MRSA in patients with hospital acquired infection and to identify alternate cost effective antibiotics.METHODS:
A six month study was carried out for 50 patients with MRSA infection. Treatment modalities and risk factors were determined by a preset protocol. Minimum inhibitory concentration of commonly used antibiotics was determined.RESULTS:
The risk factors were prolonged postoperative morbidity, prior antibiotic therapy and emergency admissions. Seventy percent of the isolates were from postoperative cases undergoing emergency surgeries. Isolation was highest during the second week of hospital stay. Emergency admissions had a significantly higher chance of early isolation. Prior treatment with multiple antibiotics in 38% was found to be another major risk factor. Ofloxacin was seen to be efficacious in a small percentage of cases. Rifampicin in combination with ofloxacin and clindamycin were found to be other good alternatives. Ofloxacin was found to be the cheapest and vancomycin the most expensive, for a full course of treatment.CONCLUSIONS:
Minimizing risk factors and attention to alternate cost effective combination therapy may ease the problem of management of infections with MRSA.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Infecciones Estafilocócicas
/
Staphylococcus aureus
/
Humanos
/
Pruebas de Sensibilidad Microbiana
/
Infección Hospitalaria
/
Factores de Riesgo
/
Resistencia a la Meticilina
/
Farmacorresistencia Bacteriana
/
Quimioterapia Combinada
/
Antibacterianos
Tipo de estudio:
Estudio de etiología
/
Guía de Práctica Clínica
/
Estudio pronóstico
/
Factores de riesgo
Idioma:
Inglés
Revista:
Indian J Med Microbiol
Asunto de la revista:
Microbiology
Año:
2006
Tipo del documento:
Artículo
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