Serological evaluation of leptospirosis in Hyderabad Andhra Pradesh: a retrospective hospital-based study.
Indian J Med Microbiol
;
2007 Jan; 25(1): 24-7
Artículo
en Inglés
| IMSEAR
| ID: sea-53812
ABSTRACT
PURPOSE:
Leptospirosis is a zoonotic disease with humans getting the infection either from rodent hosts or from domestic animals. Urine contaminated environment is the common source of infection. This is an under-reported disease in Andhra Pradesh. We report a retrospective hospital-based study on 55 patients with suspected leptospirosis.METHODS:
A total of 55 serum samples were collected from patients with suspected leptospirosis and subjected to serological testing by LeptoTek Dri-dot, microscopic agglutination test (MAT) and IgM enzyme-linked immunosorbent assay (ELISA). Identification of the predominant infecting serotype was done using a panel of 12 serovars.RESULTS:
MAT analysis of all the 55 samples identified all cases to be positive. The predominant serogroup was Icterohaemorrhagiae (68%) followed by Australis (22%), Autumnalis (8%) and Javanica (2%). LeptoTek Dri-dot showed a sensitivity of 96% as compared to MAT. IgM ELISA done on 32 samples showed a sensitivity of 86.7% compared to MAT.CONCLUSIONS:
MAT helped to identify Icterohemorrhagiae as the predominant serovar in this study. Despite the small number of samples analyzed, the data obtained establishes a need for a prospective study in this region.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Humanos
/
Inmunoglobulina M
/
Ensayo de Inmunoadsorción Enzimática
/
Pruebas de Hemaglutinación
/
Pruebas Serológicas
/
Células Cultivadas
/
Estudios Retrospectivos
/
Hospitales
/
India
/
Leptospira
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
Indian J Med Microbiol
Asunto de la revista:
Microbiology
Año:
2007
Tipo del documento:
Artículo
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