Antigeneic cross-reactivity between ICRC-bacilli and M. leprae--"in vitro" evaluation.
Indian J Lepr
;
1984 Apr-Jun; 56(2): 219-31
Artículo
en Inglés
| IMSEAR
| ID: sea-54495
ABSTRACT
Leucocyte migration inhibition, in presence of specific particulate antigen, is a good correlate of CMI. It can detect small differences in related antigens. In the present study, LMI was used to study the cross-reactivity between ICRC bacilli and M. leprae and also to examine the antigenic relationship amongst different ICRC isolates. The study showed a close antigenic cross-reactivity in lepromin and ICRC-in. LMI has brought out strain differences in two ICRC culture isolates, C-44 and C-75. The data appear to elucidate the possible strain specific antigenic relationship of M. leprae with its culture isolate e.g. ICRC strains. This may have important bearing on the development effective antileprosy vaccine for human use.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Bazo
/
Femenino
/
Inhibición de Migración Celular
/
Vacunas Bacterianas
/
Vacuna BCG
/
Reacciones Cruzadas
/
Lepromina
/
Lepra
/
Leucocitos
/
Animales
Idioma:
Inglés
Revista:
Indian J Lepr
Asunto de la revista:
Tropical Medicine
Año:
1984
Tipo del documento:
Artículo
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