Detection of subclinical infection in leprosy: an 8 years follow-up study.
Indian J Lepr
;
1989 Oct; 61(4): 495-502
Artículo
en Inglés
| IMSEAR
| ID: sea-54916
ABSTRACT
A follow-up study has been carried out using Fluorescent Leprosy Antibody Absorption (FLA-ABS) test in 1069 healthy contacts of multi and pauci-bacillary leprosy patients. Simultaneously lepromin testing with Dharmendra antigen has also been done to determine their delayed type hypersensitivity. In nearly 8 years of follow-up, 46 contacts have developed disease and of these 41 contacts were FLA-ABS positive and lepromin negative. It is inferred that test (along with lepromin) can be used to identify the contacts who are at higher risk of developing the disease. FLA-ABS test has also been found to be highly sensitive for detection of subclinical infection specially in younger age groups. This test could therefore serve as a very sensitive epidemiological tool for assessing the extent of disease in the community and for monitoring the transmission of disease especially after MDT and other intervention measures.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Humanos
/
Niño
/
Preescolar
/
Estudios de Seguimiento
/
Técnica del Anticuerpo Fluorescente
/
Adolescente
/
Lactante
/
Lepromina
/
Lepra
Tipo de estudio:
Estudio diagnóstico
/
Estudio observacional
/
Estudio pronóstico
/
Factores de riesgo
Idioma:
Inglés
Revista:
Indian J Lepr
Asunto de la revista:
Tropical Medicine
Año:
1989
Tipo del documento:
Artículo
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