Genotoxic effects of poly-D-lysine in m-AMSA (amsacrine) treated Chinese hamster ovary (CHO) cells.
Indian J Exp Biol
;
1997 Jun; 35(6): 658-60
Artículo
en Inglés
| IMSEAR
| ID: sea-55844
ABSTRACT
Cultured Chinese hamster ovary (CHO) cells were pre-treated with m-AMSA (amsacrine) and post-treated with different doses of polycationic compound poly-D-lysine (PDL) during G2 period in order to test on the frequency of chromatid-type aberrations. The present results indicate that PDL enhances the genotoxic action of m-AMSA measured as induced chromatid aberrations.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Polilisina
/
Amsacrina
/
Cricetinae
/
Células CHO
/
ADN-Topoisomerasas de Tipo II
/
Inhibidores Enzimáticos
/
Animales
/
Mutágenos
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1997
Tipo del documento:
Artículo
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