Protective role of allicin and L-ascorbic acid against the genotoxic damage induced by chlormadinone acetate in cultured human lymphocytes.
Indian J Exp Biol
;
2005 Sep; 43(9): 769-72
Artículo
en Inglés
| IMSEAR
| ID: sea-55846
ABSTRACT
In our present study, different doses of allicin and L-ascorbic acid were tested against the genotoxic damage induced by chlormadinone acetate (CMA; 40 microM) using chromosomal aberrations (CAs) and sister chromatid exchanges (SCEs) as the parameters. Treatment with allicin and L-ascorbic acid resulted in reduction of CAs and SCEs. The results suggested a protective role of allicin and L-ascorbic acid against CMA induced genotoxic damage.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ácido Ascórbico
/
Intercambio de Cromátides Hermanas
/
Ácidos Sulfínicos
/
Factores de Tiempo
/
Humanos
/
Linfocitos
/
Células Cultivadas
/
Acetato de Clormadinona
/
Depuradores de Radicales Libres
/
Aberraciones Cromosómicas
Tipo de estudio:
Estudio pronóstico
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2005
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS