Pharmacodynamic studies on Polypodium vulgare (Linn.).
Indian J Exp Biol
;
1989 Jun; 27(6): 556-60
Artículo
en Inglés
| IMSEAR
| ID: sea-55895
ABSTRACT
Aqueous extract of the root of P. vulgare (PV) produced CNS depressant effect. It decreased the spontaneous motor activity, prolonged the pentobarbitone induced hypnosis, reduced body temperature and increased the reaction time to pain stimuli. PV also caused prevention against supramaximal electroshock and pentylenetetrazol induced seizures. PV showed a positive inotropic and chronotropic effect on perfused frog heart and caused hypotension and tachycardia in anaesthetised dogs. The effects were blocked by propranolol. PV produced dose dependent inhibition of contractions of rabbit small intestine and the effect was blocked by propranolol. PV appears to possess CNS depressant and beta-adrenoceptor agonistic activities.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Plantas Medicinales
/
Ratas
/
Ratas Endogámicas
/
Presión Sanguínea
/
Femenino
/
Masculino
/
Extractos Vegetales
/
Depresores del Sistema Nervioso Central
/
Sistema Nervioso Central
/
Perros
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1989
Tipo del documento:
Artículo
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