Hypolipidemic activity of Achyranthus aspera Linn in normal and triton induced hyperlipemic rats.
Indian J Exp Biol
;
1992 Feb; 30(2): 128-30
Artículo
en Inglés
| IMSEAR
| ID: sea-55918
ABSTRACT
The alcoholic extract of A. aspera, at 100 mg/kg dose lowered serum cholesterol (TC), phospholipid (PL). triglyceride (TG) and total lipids (TL) levels by 60, 51, 33 and 53% respectively in triton induced hyperlipidemic rats. The chronic administration of this drug at the same doses to normal rats for 30 days, lowered serum TC, PL, TG and TL by 56, 62, 68 and 67% respectively followed by significant reduction in the levels of hepatic lipids. The faecal excretion of cholic acid and deoxycholic acid increased by 24 and 40% respectively under the action of this drug. The possible mechanism of action of cholesterol lowering activity of A. aspera may be due to rapid excretion of bile acids causing low absorption of cholesterol.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Fosfolípidos
/
Plantas Medicinales
/
Polietilenglicoles
/
Ratas
/
Ratas Endogámicas
/
Triglicéridos
/
Masculino
/
Extractos Vegetales
/
Colesterol
/
Metabolismo de los Lípidos
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1992
Tipo del documento:
Artículo
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