Reversal of angiotensin converting enzyme (ACE) inhibitor induced vasodilatation by vasopressin in hindquarters of rat.
Indian J Exp Biol
;
1990 Oct; 28(10): 992-3
Artículo
en Inglés
| IMSEAR
| ID: sea-55926
ABSTRACT
The effect of exogenously administered vasopressin was observed on captopril induced vasodilatation in hindquarters of anaesthetised rats. Drops of perfusate were counted for 6 min and mean of the outflow was expressed as drops per min (dpm). In the control group (n = 6) the rate of flow was 9.5 +/- 1.04 dpm which increased to 12.33 +/- 1.36 dpm following captopril (200 micrograms/ml) infusion. In test group (n = 6) pretreated with vasopressin (4 I.U./kg 1 hr before) the rate of flow was 9.16 +/- 0.98 dpm which was reduced to 5.5 +/- 1.04 dpm following infusion with captopril. It is concluded that vasopressin reverses the vasodilatory effect of captopril.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Ratas Endogámicas
/
Vasodilatación
/
Femenino
/
Masculino
/
Vasopresinas
/
Captopril
/
Animales
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1990
Tipo del documento:
Artículo
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