Effect of medroxy progesterone acetate and testosterone enanthate on vas deferens of rats.
Indian J Exp Biol
;
1998 Feb; 36(2): 157-61
Artículo
en Inglés
| IMSEAR
| ID: sea-56160
ABSTRACT
Effects of medroxy progesterone acetate (MPA; 5 mg/kg) and MPA + testosterone enanthate (TE) (3 mg + 2 mg/kg) were investigated in vas deferens and on fertility (along with reversibility study) for 60 days through histopathology, morphometric and certain biochemical parameters such as total proteins, sialic acid, ATPase, SDH and testosterone. The study revealed for altered histopathology and contratile pattern of vas deferens resulting in reduced fertility. The study also indicated androgen antagonistic effect. These effects were found to be reversible 4 and 3 months after withdrawal of MPA and MPA + TE injections respectively. Thus, both types generated functional sterility in the rat, but MPA affected histophysiology of vasal tissue.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Recuento de Espermatozoides
/
Motilidad Espermática
/
Testosterona
/
Conducto Deferente
/
Masculino
/
Acetato de Medroxiprogesterona
/
Fertilidad
/
Animales
/
Contracción Muscular
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1998
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS