Neuroprotective effects of vitamin E in cold induced cerebral injury in guinea pigs.

Badhe, Prerna; Thorat, Jayant; Diyora, Batuk D; Mamidanna, Ravikrishna; Sayal, Parag; Badhe, Suvarna; Sharma, Alok K

Badhe, Prerna; Thorat, Jayant; Diyora, Batuk D; Mamidanna, Ravikrishna; Sayal, Parag; Badhe, Suvarna; Sharma, Alok K.

Indian J Exp Biol ; 2007 Feb; 45(2): 180-4

Artículo en Inglés | IMSEAR | ID: sea-56371

ABSTRACT

ABSTRACT

Significant reduction in hemorrhage (10 v/s 13), necrosis (2 v/s 4), cavitations (7 v/s 13), neuronal degeneration, perivascular and parenchymal inflammatory infiltrate (7 v/s 11) were observed in Vitamin E treated cold induced head injury in guinea pigs, evaluated post injury using the modified Benderson's scale. The results suggest that Vitamin E is highly effective in promoting clinical and histopathological recovery in cold induced head injury in guinea pigs.

Asunto(s)

Animales; Antioxidantes/uso terapéutico; Encéfalo/patología; Lesiones Encefálicas/tratamiento farmacológico; Frío; Femenino; Cobayas; Masculino; Fármacos Neuroprotectores/uso terapéutico; Distribución Aleatoria; Vitamina E/uso terapéutico

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Vitamina E / Encéfalo / Lesiones Encefálicas / Femenino / Masculino / Distribución Aleatoria / Frío / Fármacos Neuroprotectores / Cobayas / Animales Idioma: Inglés Revista: Indian J Exp Biol Año: 2007 Tipo del documento: Artículo

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