Toxic effects of different concentrations of dimethoate on lysosomal enzymes of female albino rats.
Indian J Exp Biol
;
1992 May; 30(5): 394-8
Artículo
en Inglés
| IMSEAR
| ID: sea-56408
ABSTRACT
The effect of three different concentrations of dimethoate on the activity of certain lysosomal enzymes, viz. beta-glucuronidase, beta-N-acetylglucosaminidase, cathepsin B and cathepsin D in serum, skin, liver, kidney and spleen and the stability of liver and kidney lysosomes was studied in female albino rats. The activity of beta-glucuronidase, beta-N-acetylglucosaminidase, cathepsin D was found to increase in serum and tissues in higher concentration (2.25 mg/100 g body weight) of dimethoate treated rats. A significant increase in the rate of release of beta-glucuronidase was found in the liver and kidney of higher concentration of dimethoate treated rats compared to controls. The results demonstrate that the activity of lysosomal enzymes increased in higher concentration of dimethoate treated rats than the lower concentration (0.56 mg/100 g body weight) of dimethoate treated rats.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Piel
/
Vísceras
/
Femenino
/
Ratas Wistar
/
Dimetoato
/
Relación Dosis-Respuesta a Droga
/
Animales
/
Lisosomas
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1992
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS