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Effect of Azadirachta indica leaves on testis and its recovery in albino rats.
Indian J Exp Biol ; 1996 Nov; 34(11): 1091-4
Artículo en Inglés | IMSEAR | ID: sea-56542
ABSTRACT
Histological and biochemical changes in the testis of rats treated with the leaf powder of A. indica are reported. The pattern of recovery is also studied at 8, 16 and 24 day after withdrawal of the treatment. In the treated rats, a general reduction in the diameters of seminiferous tubule, nuclei of the germinal elements and a mass atrophy of the spermatogenic elements has been observed. The Leydig cells are found to be atrophic. Biochemically, a decrease in the protein content and the activity of acid phosphatase and an increase in the total free sugar, glycogen, cholesterol contents and the activities of alkaline phosphatase and lactate dehydrogenase have been observed. A gradual recovery is observed in both the histological and biochemical parameters after 8.16 and 24 day of cessation of the treatment. The result suggest a possible reversible antiandrogenic property of the leaves of A. indica in male albino rats.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Plantas Medicinales / Plantas Tóxicas / Ratas / Testículo / Factores de Tiempo / Masculino / Extractos Vegetales / Ratas Wistar / Antagonistas de Andrógenos / Animales Idioma: Inglés Revista: Indian J Exp Biol Año: 1996 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Plantas Medicinales / Plantas Tóxicas / Ratas / Testículo / Factores de Tiempo / Masculino / Extractos Vegetales / Ratas Wistar / Antagonistas de Andrógenos / Animales Idioma: Inglés Revista: Indian J Exp Biol Año: 1996 Tipo del documento: Artículo