Post-metaphase mitotic events in cells treated with dinitrophenol.
Indian J Exp Biol
;
1989 Apr; 27(4): 317-23
Artículo
en Inglés
| IMSEAR
| ID: sea-56590
ABSTRACT
The sequence of post-metaphase mitotic events, such as anaphase movement A and B, chromosome decondensation, nuclear envelope reformation and cytokinesis, has been studied in 2,4-initrophenol (DNP)-treated HeLa cells. The effects of DNP were found to be dose dependent and at concentrations higher than 3 mM, both anaphase A and B movements were totally and nearly instantaneously arrested. It could be shown that cytokinesis did not depend on the completion of anaphase movements. This was also true for nuclear envelope reformation which could take place even around condensed chromosomes arrested in anaphase. The post-metaphase mitotic events do not follow a strict causal sequence, but they can be dissociated from each other in anaphase-arrested cells.
Texto completo:
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Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Humanos
/
Células HeLa
/
Microscopía Electrónica
/
División Celular
/
Cromosomas
/
2,4-Dinitrofenol
/
Dinitrofenoles
/
Relación Dosis-Respuesta a Droga
/
Anafase
/
Animales
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1989
Tipo del documento:
Artículo
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