Characterization of dopamine receptors involved in central thermoregulation in rabbits.
Indian J Exp Biol
;
1991 Nov; 29(11): 1087-8
Artículo
en Inglés
| IMSEAR
| ID: sea-56886
ABSTRACT
Intracerebroventricularly administered dopamine produced dose dependent hyperthermia in rabbits. Haloperidol, a D1 receptor blocker produced consistent hypothermia, whereas D2 receptor blocker metoclopramide produced hyperthermia, pretreatment with haloperidol competitively blocked the hyperthermic response of dopamine. Pretreatment with metoclopramide augmented the onset and peak response of dopamine. It is suggested that D1 receptors are involved in producing hyperthermia and D2 receptors in hypothermia.
Texto completo:
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Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Conejos
/
Regulación de la Temperatura Corporal
/
Femenino
/
Masculino
/
Receptores Dopaminérgicos
/
Haloperidol
/
Animales
/
Metoclopramida
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1991
Tipo del documento:
Artículo
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