Effects of photofrin II and light on cellular adenine nucleotides and their modulation.
Indian J Exp Biol
;
1997 Apr; 35(4): 356-60
Artículo
en Inglés
| IMSEAR
| ID: sea-57209
ABSTRACT
Effects of photofrin II (PII) and light on the intra cellular nucleotide levels have been investigated using BHK-21 cell line. Results indicate that lower concentrations of photofrin II in dark increases ATP levels in a non linear manner, however, there has been no change in energy charge and levels of other nucleotides. Photoirradiation of PII-treated cells leads to a significant reduction in ATP levels and energy charge along with an increase in ATP breakdown products like ADP and AMP. The phosphorylation potential [ATP]/[ADP][Pi] also reduces upon photoirradiation of PII treated cells. Incubation conditions like pH of the medium and temperature modulate the cellular responses to a great extent.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Fotoquimioterapia
/
Temperatura
/
Nucleótidos de Adenina
/
Línea Celular
/
Cricetinae
/
Éter de Dihematoporfirina
/
Metabolismo Energético
/
Concentración de Iones de Hidrógeno
/
Luz
/
Animales
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1997
Tipo del documento:
Artículo
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