Genotoxic effect of isoproturon (herbicide) as revealed by three mammalian in vivo mutagenic bioassays.
Indian J Exp Biol
;
1990 Sep; 28(9): 862-7
Artículo
en Inglés
| IMSEAR
| ID: sea-57253
ABSTRACT
Genotoxic effect of isoproturon was assessed by employing in vivo chromosomal aberration, micronucleus and sperm-shape abnormality assays. A significant dose-responsive mutagenic effect was observed in chromosome aberration and sperm-shape abnormality tests whereas in micronucleus assay the effect was significant only at the highest dose (200 mg/kg). Only the result for the chronic dose and the two different fixation times (6 and 48 hr) were not statistically significant. The results indicate the genotoxic property of isoproturon in mammalian in vivo test system.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Compuestos de Fenilurea
/
Espermatozoides
/
Masculino
/
Células de la Médula Ósea
/
Pruebas de Micronúcleos
/
Análisis de Varianza
/
Aberraciones Cromosómicas
/
Herbicidas
/
Animales
/
Compuestos de Metilurea
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1990
Tipo del documento:
Artículo
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