Sex differences in oxidative stress induced by benzene in rats.

Verma, Yeshvandra; Rana, S V S

Verma, Yeshvandra; Rana, S V S.

Indian J Exp Biol ; 2004 Jan; 42(1): 117-20

Artículo en Inglés | IMSEAR | ID: sea-57658

ABSTRACT

ABSTRACT

Role of sex differences on oxidative stress induced by benzene has been studied in liver, kidney and lungs of rat. It was observed that benzene administration enhanced lipid peroxidation in liver, kidney and lungs of rat, nevertheless, significant variations were recorded in male and female rats. Decrease of GSH and CYTP(450)2E1 was higher in female rats than male rats except lungs. The results suggest that oxidative stress induced by benzene is higher in female rats.

Asunto(s)

Animales; Benceno/farmacología; Citocromo P-450 CYP2E1/metabolismo; Femenino; Glutatión/metabolismo; Riñón/metabolismo; Peroxidación de Lípido; Hígado/metabolismo; Pulmón/metabolismo; Masculino; Oxidación-Reducción; Estrés Oxidativo; Ratas; Factores Sexuales

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Oxidación-Reducción / Ratas / Benceno / Femenino / Masculino / Peroxidación de Lípido / Factores Sexuales / Estrés Oxidativo / Citocromo P-450 CYP2E1 / Glutatión Idioma: Inglés Revista: Indian J Exp Biol Año: 2004 Tipo del documento: Artículo

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