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Electromagnetic exposure effects the hippocampal dentate cell proliferation in gerbils (Meriones unguiculatus).
Indian J Exp Biol ; 2001 Dec; 39(12): 1220-6
Artículo en Inglés | IMSEAR | ID: sea-57745
ABSTRACT
The chronic effect on hippocampal neurogenesis after exposure (30 min/day for 14 days) to a high frequency (35,53 kHz) electromagnetic field, double modulated at extremely low frequencies (ELF; 1, 8, 12, 29 and 50 Hz), was studied in young adult gerbils. Immediately after the last exposure proliferation of dentate granule cells was identified by in vivo labeling with 5-bromo-2-desoxyuridine (BrdU). Exposure to 1, 29 and 50 Hz resulted in a statistically significant reduction of cell proliferation rates, but only the 50 Hz-group manifested the effect highly significantly (-29,3 %). On the other hand, gerbils exposed to 8 and 12 Hz showed no significant change of postmitotic cell proliferation as compared with the sham treated controls. The results suggest that the effects of ELF on the granule cell proliferation are mediated by neurotransmitters and hormones which regulate hippocampal neurogenesis.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Masculino / División Celular / Gerbillinae / Giro Dentado / Campos Electromagnéticos / Animales Idioma: Inglés Revista: Indian J Exp Biol Año: 2001 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Masculino / División Celular / Gerbillinae / Giro Dentado / Campos Electromagnéticos / Animales Idioma: Inglés Revista: Indian J Exp Biol Año: 2001 Tipo del documento: Artículo