Evaluation of methanolic extract of Ficus platyphylla on gastrointestinal activity.
Indian J Exp Biol
;
2001 Jan; 39(1): 63-7
Artículo
en Inglés
| IMSEAR
| ID: sea-57938
ABSTRACT
Methanolic extract of Ficus platyphylla was tested on isolated rabbit jejunum, rat duodenum and gastrointestinal motility in mice. The extract showed a biphasic effect on isolated smooth muscle. Lower concentration of extract caused contraction, while higher concentrations produced relaxation. The contractile phase was attenuated by atropine, while relaxant phase attenuated histamine induced contraction of guinea pig ileum. The extract also exhibited a dose-dependent inhibition of gastrointestinal motility. Acute toxicity test in mice established LD50 value (i.p.) of the extract to be 2000 mg/kg. Preliminary phytochemical screening of the extract gave positive test for flavonoids, tannins and saponins.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Conejos
/
Ratas
/
Femenino
/
Masculino
/
Tránsito Gastrointestinal
/
Extractos Vegetales
/
Ratas Wistar
/
Rosales
/
Sistema Digestivo
/
Relación Dosis-Respuesta a Droga
Tipo de estudio:
Estudios de evaluación
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2001
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS