Use of adjuvants in modulating the behaviour of Plasmodium berghei.
Indian J Exp Biol
;
1990 Dec; 28(12): 1112-7
Artículo
en Inglés
| IMSEAR
| ID: sea-58128
ABSTRACT
Different adjuvants were assessed for their role in conferring protection against the rodent malarial parasite P. berghei and compared with the classical Freund's complete adjuvant (FCA). Pretreatment of mice with trehalose dimycolate (TDM) mixed with antigen (Ag), sulpholipids (SL) mixed with Ag, muramyl dipeptide (MDP) alone, liposomes containing Ag and phosphomannoinositides (PIM) mixed with Ag were ineffective in conferring protection. However, MDP given with squalane (Sq) and Ag, MDP with incomplete Freund's adjuvant (IFA) and Ag, palmitoyl-MDP with Sq and Ag, aluminium hydroxide adsorbed Ag, and FCA with Ag were effective in conferring varying degrees of protection to mice. Complete protection in rats was obtained with MDP mixed with Sq and Ag, and FCA mixed with Ag, and a partial protection with liposomes containing Ag.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Plasmodium berghei
/
Ratas
/
Ratas Endogámicas
/
Femenino
/
Masculino
/
Adyuvantes Inmunológicos
/
Animales
/
Malaria
/
Ratones
/
Ratones Endogámicos
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1990
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS