Effectiveness of ethylene glycol bis (2-aminoethyl ether) tetraacetic acid (EGTA) against cerium toxicity.
Indian J Exp Biol
;
2004 Sep; 42(9): 876-83
Artículo
en Inglés
| IMSEAR
| ID: sea-58211
ABSTRACT
Therapeutic efficacy of EGTA (ethylene glycol bis (2-aminoethyl ether) tetraacetic acid) against cerium intoxicated mice was studied. Administration of cerium showed significant decrease in haemoglobin percentage, RBC counts and blood glucose level with an increase in the activity of serum transaminases and WBC counts. Decrease in the activity of alkaline phosphatase and glycogen content was noted in liver and kidney after cerium exposure. Light and electron microscopical investigations showed that these changes were recouped considerably with the administration of EGTA suggesting its therapeutic efficacy against cerium toxicity.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Glucemia
/
Masculino
/
Hemoglobinas
/
Cerio
/
Quelantes
/
Ácido Egtácico
/
Fosfatasa Alcalina
/
Recuento de Eritrocitos
/
Amidinotransferasas
/
Glucógeno
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2004
Tipo del documento:
Artículo
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