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Modulatory effect of quercetin on azathioprine induced membrane changes in the mouse spleen.
Indian J Exp Biol ; 2001 Feb; 39(2): 132-6
Artículo en Inglés | IMSEAR | ID: sea-58626
ABSTRACT
Modulatory effect of quercetin on azathioprine induced toxic changes was studied in spleen of experimental animals. Azathioprine treatment caused an increase in serum albumin/globin ratio and a decrease in total protein in spleen tissue. An increase in a membrane bound ATPases was also noted. Supplementation of quercetin with azathioprine increased the protein content and lowered the activities of membrane ATPase in spleen. There was a decrease in serum albumin globulin ratio. It was concluded that quercetin modulated the protein and membrane bound ATPase activities and protected the spleen from azathioprine induced membrane damage.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Quercetina / Bazo / Azatioprina / Masculino / Albúmina Sérica / Membrana Celular / Adenosina Trifosfatasas / Globulinas / Animales / Ratones Idioma: Inglés Revista: Indian J Exp Biol Año: 2001 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Quercetina / Bazo / Azatioprina / Masculino / Albúmina Sérica / Membrana Celular / Adenosina Trifosfatasas / Globulinas / Animales / Ratones Idioma: Inglés Revista: Indian J Exp Biol Año: 2001 Tipo del documento: Artículo