Apoptosis in endometrium of mouse during estrous cycle.
Indian J Exp Biol
;
2001 Mar; 39(3): 218-22
Artículo
en Inglés
| IMSEAR
| ID: sea-58642
ABSTRACT
The present study was carried out to evaluate apoptosis in endometrium and to correlate these changes with the circulating levels of estradiol and progesterone in the mouse. Apoptosis was observed in various compartments of mouse uterus i.e. stroma, glandular epithelium and luminal epithelium depending on the stage of cycle. Stromal cell apoptosis was observed during various stages of cyclicity except on estrus day. Luminal epithelial cells showed apoptotic changes during all stages of cyclicity except on diestrus day. During metestrus, apoptosis was observed in glandular and luminal epithelia as well as stromal cells. Steroid antagonists such as tamoxifen and onapristone altered the apoptotic changes in the uterus. The results suggest that epithelial cell apoptosis is regulated by estrogen while stromal cell apoptosis is under the control of progesterone.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Progesterona
/
Femenino
/
Estro
/
Células del Estroma
/
Apoptosis
/
Endometrio
/
Células Epiteliales
/
Estradiol
/
Animales
/
Ratones
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2001
Tipo del documento:
Artículo
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