Lipid peroxidation and antioxidant enzymes in erythrocytes and tissues in aged diabetic rats.
Indian J Exp Biol
;
1997 Apr; 35(4): 389-92
Artículo
en Inglés
| IMSEAR
| ID: sea-58689
ABSTRACT
Antidiabetic treatment with powdered fruit of Capparis decidua decreased alloxan induced lipid peroxidation (LPO) significantly in erythrocytes, kidney and heart. Erythrocyte superoxide dismutase (SOD) activity decreased while the kidney and heart SOD increased in diabetic animals. These alterations in SOD were counteracted by insulin as well as with powdered fruit of C. decidua. Increased catalase (CAT) activity in erythrocytes, liver, kidney and heart with C. decidua treatment indicate that the treatment may neutralize H2O2 toxicity by its increased decomposition by CAT. Result shows that treatment with C. decidua lowers alloxan induced LPO and alters SOD and CAT enzymes to reduce oxidative stress.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Superóxido Dismutasa
/
Masculino
/
Envejecimiento
/
Peroxidación de Lípido
/
Catalasa
/
Ratas Wistar
/
Estrés Oxidativo
/
Diabetes Mellitus Experimental
/
Eritrocitos
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1997
Tipo del documento:
Artículo
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