Role of 5-hydroxytryptamine in Moringa oleifera induced potentiation of pentobarbitone hypnosis in albino rats.
Indian J Exp Biol
;
2004 Jun; 42(6): 632-5
Artículo
en Inglés
| IMSEAR
| ID: sea-58833
ABSTRACT
The role of 5-hydroxytryptamine (5-HT) in pentobarbitone (PB) sleeping time, gross behaviour, electrical activity of the brain and serum 5-HT level was studied in Holtzman strain adult albino rats following treatment with M. oleifera (MO). MO (350mg/kg) caused inhibition of awareness, touch response, motor activity, righting reflex, and grip strength. It significantly increased the PB sleeping time, serum 5-HT level (P<0.001) and alpha-wave activity. These observations indicate that the aqueous extract of MO potentiated PB induced sleeping time and increased the alpha-wave activity through 5-HT.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Pentobarbital
/
Ratas
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Sueño
/
Factores de Tiempo
/
Conducta Animal
/
Encéfalo
/
Femenino
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Masculino
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Serotonina
/
Depuradores de Radicales Libres
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2004
Tipo del documento:
Artículo
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