Effect of some Sitavirya drugs on gastric secretion and ulceration.
Indian J Exp Biol
;
1997 Oct; 35(10): 1084-7
Artículo
en Inglés
| IMSEAR
| ID: sea-58946
ABSTRACT
Four Sitavirya plants viz. Satavari (fresh root juice, 1250 mg/kg), Yastimadhu (water decoction of root, 600 mg/kg), Kutaja and Aswattha (water decoctions of bark; 400 and 500 mg/kg respectively) were studied for their effects on different models of gastroduodenal ulcers in rats, when given orally for 3 days. All of them were found to protect the animals against 2 hr cold restraint stress and pylorus ligation-induced gastric and cysteamine-induced duodenal ulcers. However, they were ineffective against acute aspirin-induced gastric ulcers. The antiulcerogenic effect could be due to their inhibitory effect on offensive acid-pepsin secretion and augmentation of mucosal defensive factors in terms of enhanced mucin secretion and decreased cell shedding.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Úlcera Péptica
/
Plantas Medicinales
/
Ratas
/
Tasa de Secreción
/
Femenino
/
Masculino
/
Evaluación Preclínica de Medicamentos
/
Mucosa Gástrica
/
Animales
/
Antiulcerosos
Tipo de estudio:
Estudio pronóstico
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1997
Tipo del documento:
Artículo
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