p-Aminobenzene sulphonyl morpholine, compound 82/208 a new anticonvulsant agent.
Indian J Exp Biol
;
1994 Oct; 32(10): 729-31
Artículo
en Inglés
| IMSEAR
| ID: sea-59155
ABSTRACT
p-Aminobenzene sulphonyl morpholine, compound 82/208, was evaluated for acute toxicity and anticonvulsant action in mice against tonic seizures induced by supramaximal electroshock and pentylene tetrazole and strychnine induced seizures and for its effect on blood pressure and respiration in cat. Diphenyl hydantoin (DPH) was used as reference standard. Compound 82/208 exhibited anticonvulsant activity against electroshock induced seizures and PTZ induced tonic seizures in mice. The compound had several distinct advantages over DPH in experimental evaluation in mice.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Fenitoína
/
Sulfanilamidas
/
Femenino
/
Masculino
/
Evaluación Preclínica de Medicamentos
/
Animales
/
Ratones
/
Anticonvulsivantes
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1994
Tipo del documento:
Artículo
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