Propagation of Chandipura virus in chick embryos.
Indian J Exp Biol
;
2005 Oct; 43(10): 930-2
Artículo
en Inglés
| IMSEAR
| ID: sea-59209
ABSTRACT
Stocks of three Indian Chandipura virus (CHPV) isolates; one isolate from an adult febrile case in 1965 from Chandipura town, Maharashtra, and two isolates from two pediatric encephalitis cases from Andhra Pradesh, 2003 were inoculated in 10-day-old chick embryos by allantoic route. All three virus isolates replicated in chick embryos showing titre of log 10(12) to log 10(13) EID50. The results demonstrated that chick embryos are susceptible to CHPV and virus grows to high titres in this system. Therefore chick embryos can be used as an alternative host system for cultivation and isolation of CHPV as they are less expensive than laboratory animals and have several other advantages over cell cultures. Also this system can be used for the development of vaccine and diagnostic reagents.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Cultivo de Virus
/
Humanos
/
Microscopía Electrónica
/
Vesiculovirus
/
Concentración 50 Inhibidora
/
Técnicas de Cultivo
/
Animales
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2005
Tipo del documento:
Artículo
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