In vitro effect of lorazepam on Mg2+ and (Na+,K+) ATPases of human foetal brain.
Indian J Exp Biol
;
1989 Jan; 27(1): 44-6
Artículo
en Inglés
| IMSEAR
| ID: sea-59503
ABSTRACT
Lorazepam (LZ), a benzodiazepine group of drug, inhibits Mg2+ and (Na+,K+) ATPases (EC 3.6.1.3) activity of human foetal and adult brain. The inhibitory effect neither varied with respect to the region (i.e. cerebrum and cerebellum) nor with the age of the foetus. The inhibition of ATPases activity indicates that the neuronal transmission processes, may be affected and raises the possibility of developmental disturbances.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Encéfalo
/
Humanos
/
ATPasa de Ca(2/) y Mg(2/)
/
ATPasa Intercambiadora de Sodio-Potasio
/
Feto
/
Lorazepam
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1989
Tipo del documento:
Artículo
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