Virus enhancement following infection with antibody-coated infectious bursal disease virus (IBDV) in chickens.
Indian J Exp Biol
;
2001 Dec; 39(12): 1314-7
Artículo
en Inglés
| IMSEAR
| ID: sea-59584
ABSTRACT
A novel concept of vaccination, employing virus-antibody complex has been reported for the control of infectious bursal disease in chickens. A comparison of virus replication, serum neutralizing antibody response and pathogenicity in chickens inoculated with the antibody coated virus, prepared by mixing virus and antibody in different ratios (11, 10.1, 1 0.01) and virus alone without antibody, has been made. Antibody coated virus (when mixed in certain crucial ratios) replicated to a higher magnitude in the target organ, caused more severe pathogenesis but induced a primary serum neutralizing antibody response almost comparable. The results may have important implications in understanding of pathogenesis and development of control strategies against infectious bursal disease virus, specially employing immune complex vaccine.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Pollos
/
Virus de la Enfermedad Infecciosa de la Bolsa
/
Animales
/
Anticuerpos Antivirales
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2001
Tipo del documento:
Artículo
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