Inhibition of selenium dependent glutathione peroxidase and superoxide dismutase in rats by diethyldithiocarbamate: effect of pre-administration of alpha-tocopherol.
Indian J Exp Biol
;
2007 May; 45(5): 465-8
Artículo
en Inglés
| IMSEAR
| ID: sea-60172
ABSTRACT
Rats pre-administered with alpha-tocopherol (10 mgs/day) for 7 days afforded a significant protection at the tissue level against the lowering of superoxide dismutase and glutathione peroxidase, especially the selenium-dependent glutathione peroxidase. The protective action of alpha-tocopherol in the diethyldithiocarbamate treated rats may be attributed to its antioxidant/free radical scavenging action. It is concluded that selenium-dependent glutathione peroxidase and alpha-tocopherol act in a complementary fashion to block free radical formation.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Superóxido Dismutasa
/
Factores de Tiempo
/
Masculino
/
Ratas Wistar
/
Ditiocarba
/
Citoprotección
/
Alfa-Tocoferol
/
Radicales Libres
/
Glutatión Peroxidasa
Tipo de estudio:
Estudios de evaluación
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2007
Tipo del documento:
Artículo
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