Differential amplification and expression of c-myb oncogene in Zajdela ascitic hepatoma.
Indian J Exp Biol
;
1990 May; 28(5): 401-4
Artículo
en Inglés
| IMSEAR
| ID: sea-60362
ABSTRACT
Organisation and expression of c-myb protooncogene have been studied in a heterogeneous tumour the Zajdela ascitic hepatoma (ZAH). The myb gene is selectively amplified in the more tumorigenic subpopulation of the tumour while the non-lethal subpopulation does not show any change. Analysis of transcripts of the myb gene in tumorigenic versus nontumorigenic cells shows that the level of amplification of the gene does not correspond to the level of its transcription. Results have been discussed in the light of existing evidence regarding the role of c-myb gene expression during cell cycle.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Proto-Oncogenes
/
ADN de Neoplasias
/
Expresión Génica
/
Amplificación de Genes
/
Hígado
/
Neoplasias Hepáticas Experimentales
/
Animales
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1990
Tipo del documento:
Artículo
Similares
MEDLINE
...
LILACS
LIS