Effect of gossypol on tissue levels of glutathione and thiobarbituric acid reactive products in rats.
Indian J Exp Biol
;
1992 Aug; 30(8): 734-5
Artículo
en Inglés
| IMSEAR
| ID: sea-60638
ABSTRACT
Gossypol was administered in pubertal and adult rats and lipid peroxide formation and GSH levels were estimated in different tissues like liver, testis, heart and kidney. Gossypol caused low generation of lipid peroxides, measured as thiobarbituric acid reactive products (TBAR), without causing significant changes in tissue glutathione (GSH) levels. This effect was more pronounced in liver and testis as compared to other tissues. In vitro effect of gossypol to inhibit lipid peroxidation as observed in vivo suggested that binding of gossypol to plasma membranes may result in inhibition of lipid peroxide generation.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Testículo
/
Tiobarbitúricos
/
Masculino
/
Gosipol
/
Peroxidación de Lípido
/
Factores de Edad
/
Ratas Wistar
/
Glutatión
/
Riñón
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1992
Tipo del documento:
Artículo
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