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Effect of a new herbo-mineral hypolipidemic agent on plasma lipoprotein pattern in rat atherosclerosis.
Indian J Exp Biol ; 1990 Jul; 28(7): 657-60
Artículo en Inglés | IMSEAR | ID: sea-60883
ABSTRACT
Hyperlipidemia was induced in rats by feeding an atherogenic diet for 5 months. The effect of administration of an indigenous hypolipidemic agent, Anna Kaara Raaja Sindhooram (AKRS) on the plasma lipoprotein profile was studied in the presence and absence of dietary lipid stimuli. Hyperlipidemia produced an enormous increase in the cholesterol and triglyceride contents of the low density (LDL) and very low density (VLDL) lipoprotein fractions and reduced the level of the putative non-atherogenic high density cholesterol (HDL-C). The agarose gel electrophoretic pattern showed a decrease in alpha-lipoproteins and an increase in beta-lipoproteins in the hyperlipidemic rats. AKRS treatment for 5 months altered the lipoprotein pattern favourably by raising HDL-C and lowering LDL-C in the treated rats.
Asunto(s)
Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Arteriosclerosis / Ratas / Ratas Endogámicas / Boratos / Masculino / Extractos Vegetales / Compuestos Ferrosos / Dieta Aterogénica / Lipoproteínas / Animales Idioma: Inglés Revista: Indian J Exp Biol Año: 1990 Tipo del documento: Artículo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Arteriosclerosis / Ratas / Ratas Endogámicas / Boratos / Masculino / Extractos Vegetales / Compuestos Ferrosos / Dieta Aterogénica / Lipoproteínas / Animales Idioma: Inglés Revista: Indian J Exp Biol Año: 1990 Tipo del documento: Artículo