Bone morphogenetic proteins--novel regulators of bone formation.
Indian J Exp Biol
;
1998 Mar; 36(3): 237-44
Artículo
en Inglés
| IMSEAR
| ID: sea-60938
ABSTRACT
Bone morphogenetic proteins (BMPs), hydrophobic, non-species specific glycoproteins, belong to the expanding transforming growth factor-beta (TGF-beta) superfamily. BMP has pleiotropic function that range from extraskeletal and skeletal organogenesis to bone generation and regeneration. It induces de novo bone formation in post fetal life through the process of direct (intra membranous) and endochondral ossification and their response is dose dependent. Through recombinant gene technology, BMP is available at least in ten forms for basic research and clinical trials. Amino acid sequences and physical properties of BMP family members have been identified. BMP research extends to the fields of developmental biology, genetics and evolution.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Desarrollo Óseo
/
Humanos
/
Datos de Secuencia Molecular
/
Niño
/
Secuencia de Aminoácidos
/
Proteínas Morfogenéticas Óseas
/
Adulto
/
Animales
Tipo de estudio:
Estudio pronóstico
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1998
Tipo del documento:
Artículo
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