Bidder's organ extract induced anaphylaxis in experimental animals.
Indian J Exp Biol
;
2000 Feb; 38(2): 177-9
Artículo
en Inglés
| IMSEAR
| ID: sea-61232
ABSTRACT
Bidder's organ (BO, a vestigeal organ), present in toad Bufo melanostictus (Schenider), is a characteristic feature of all male bufo. Its possible anaphylactic properties are investigated on experimental animals. BO extract produced both in vivo and in vitro anaphylactic reaction in guineapig. Dyspnoea and bronchoconstriction was a major cause of anaphylactic death. Blood histamine level was significantly increased in the anaphylactic animals. BO extract significantly released histamine from chopped lung preparation, an action antagonised by disodium chromoglycate. BO extract degranulated peritoneal mast cell in vitro. Passive cutaneous anaphylactic reactions were enhanced by BO extract and were significantly inhibited by disodium chromoglycate. Anaphylotoxin (identity not known) present in bidder's organ is probably involved in toad defence.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Conejos
/
Ratas
/
Bufonidae
/
Masculino
/
Anafilaxis Cutánea Pasiva
/
Anafilatoxinas
/
Cobayas
/
Liberación de Histamina
/
Anafilaxia
/
Pulmón
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2000
Tipo del documento:
Artículo
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