Effect of picroliv on glutathione metabolism in liver and brain of Mastomys natalensis infected with Plasmodium berghei.
Indian J Exp Biol
;
1992 Aug; 30(8): 711-4
Artículo
en Inglés
| IMSEAR
| ID: sea-61476
ABSTRACT
Administration of picroliv, the active principle from Picrorhiza kurrooa, at a dose of 6 mg/kg, po for two weeks showed significant protection against changes in liver and brain glutathione metabolism of Plasmodium berghei infected Mastomys natalensis. The depletion of reduced glutathione level and inhibition of glutathione-S-transferase, glutathione reductase and glutathione peroxidase activities due to P. berghei infection were markedly recovered by picroliv. The increased levels of lipid peroxidation products in damaged tissues were also reduced along with the recovery of glutathione metabolism.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Plasmodium berghei
/
Ácido Vanílico
/
Encéfalo
/
Masculino
/
Extractos Vegetales
/
Peroxidación de Lípido
/
Cinamatos
/
Glutatión
/
Glicósidos
/
Hígado
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1992
Tipo del documento:
Artículo
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