Prolactin suppression during pre and post-implantation periods on rat uterine glucosamine synthase activity.
Indian J Exp Biol
;
1993 Apr; 31(4): 386-8
Artículo
en Inglés
| IMSEAR
| ID: sea-61551
ABSTRACT
Administration of bromocriptine (Bc), an ergot derivative having dopamine receptor agonist activity, to rats on day 1-5 of pregnancy prevented implantation of blastocysts and significantly suppressed uterine glucosamine 6-phosphate synthase activity. There was no effect on implantation or the enzyme activity when Bc was injected on day 7 or later of pregnancy. Injection of prolactin following Bc partially restored the enzyme activity and increased number of implantation sites. These results indicate that suppression of prolactin on day 1 to 5 of pregnancy causes failure of implantation. Bc on day 9 or later had no effect possibly due to the availability of placental LH/hCG to support the luteal cells.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Implantación del Embrión
/
Prolactina
/
Ratas
/
Útero
/
Femenino
/
Embarazo
/
Bromocriptina
/
Desarrollo Embrionario
/
Glutamina-Fructosa-6-Fosfato Transaminasa (Isomerizadora)
/
Tamaño de la Camada
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1993
Tipo del documento:
Artículo
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