Effect of cyclosporin-A, antimalarial drug, on lymphocyte proliferation of Balb/c mice in vitro.
Indian J Exp Biol
;
1990 Sep; 28(9): 880-2
Artículo
en Inglés
| IMSEAR
| ID: sea-62013
ABSTRACT
Cyclosporin-A(CsA) caused inhibition of lymphocyte proliferation at higher doses (5 and 10 micrograms/ml) compared to controls. When spleen cells were preincubated with high doses of CsA and washed, the normal lymphocyte response to stimulation with mitogen (concanavalin-A) and lymphokine (interleukin-2) was not affected. The results indicate that CsA's suppressive effect at higher doses, was a temporary one and potential use of CsA to control parasitic infections should be examined.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Bazo
/
Activación de Linfocitos
/
Células Cultivadas
/
Interleucina-2
/
Concanavalina A
/
Ciclosporinas
/
Animales
/
Ratones
/
Ratones Endogámicos BALB C
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1990
Tipo del documento:
Artículo
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