Prevalence and pattern of antimicrobial resistance of Shigella species among patients with acute diarrhoea in Karaj, Tehran, Iran.
J Health Popul Nutr
;
2003 Jun; 21(2): 96-102
Artículo
en Inglés
| IMSEAR
| ID: sea-622
ABSTRACT
The study was carried out to determine the prevalence and pattern of antimicrobial resistance of Shigella species among patients with acute diarrhoea in Karaj, Tehran, Iran. The study included all acute diarrhoea patients who visited the hospitals and treatment centres of Karaj during November 2001-October 2002. Of 734 stool samples collected from patients with acute diarrhoea and analyzed for Shigella spp., 123 (16.8%) yielded Shigella spp. (7.5% Shigella flexneri, 5.2% S. sonnei, 2.6% S. dysenteriae, and 1.5% S. boydii). Of the Shigella isolates, 90.8% were resistant to one or more antimicrobial agent(s), and 87.8% were multidrug resistant. The most common resistance was to tetracycline (73.5%), trimethoprim-sulphamethoxazole (70.4%), and amoxicillin-clavulanic acid (50.0%). Resistance to cefixime, ciprofloxacin, ceftriaxone, and nalidixic acid was observed in 6.1%, 3.1%, 2.0%, and 1.0% of the isolates respectively. These findings suggest that Shigella spp. may be an important aetiological agent of diarrhoea with a high rate of drug resistance in this region, which requires further study.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Estaciones del Año
/
Shigella
/
Femenino
/
Humanos
/
Masculino
/
Recién Nacido
/
Pruebas de Sensibilidad Microbiana
/
Niño
/
Preescolar
/
Enfermedad Aguda
Tipo de estudio:
Estudio de prevalencia
País/Región como asunto:
Asia
Idioma:
Inglés
Revista:
J Health Popul Nutr
Asunto de la revista:
Gastroenterology
/
Nutritional Sciences
/
Public Health
Año:
2003
Tipo del documento:
Artículo
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