Antigenotoxic effect of allicin against SCEs induced by methyl methanesulphonate in cultured mammalian cells.
Indian J Exp Biol
;
2004 Apr; 42(4): 437-8
Artículo
en Inglés
| IMSEAR
| ID: sea-62288
ABSTRACT
Allicin, one of the sulphur compounds of garlic (Allium sativum), possesses antioxidant and thiol disulphide exchange activity and is also shown to cause a variety of activities potentially useful for human health. In this investigation, the effect of 1,5,10 and 20 microM of allicin was determined for inhibiting the rate of SCE induced by 60 microM of MMS. Cultured human lymphocytes from two female donors were used for the experiment. The levels of SCEs were lowered by allicin suggesting its antigenotoxic activity in mammalian cells in vitro.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Intercambio de Cromátides Hermanas
/
Ácidos Sulfínicos
/
Femenino
/
Humanos
/
Linfocitos
/
Células Cultivadas
/
Antineoplásicos Alquilantes
/
Metilmetanosulfonato
/
Mutágenos
/
Antioxidantes
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2004
Tipo del documento:
Artículo
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