Antiulcerogenic activity of Satavari mandur--an Ayurvedic herbo-mineral preparation.
Indian J Exp Biol
;
2002 Oct; 40(10): 1173-7
Artículo
en Inglés
| IMSEAR
| ID: sea-62428
ABSTRACT
Satavari mandur (SM) is a herbo-mineral preparation containing Asparagus racemosus, which finds mention in ancient Indian texts for treatment of gastric ulcers. The ulcer protective effect of SM, 125-500 mg/kg given orally, twice daily for three, five and seven days, was studied on cold restraint stress-induced gastric ulcer in rats. The effective regimen was found to be 250 mg/kg given for five days and hence was used for further experiments. SM showed significant protection against acute gastric ulcers induced by pyloric ligation but was ineffective against aspirin- and ethanol-induced ulcers. Further, gastric juice studies showed that, SM significantly increased the mucosal defensive factors like mucus secretion, but had little or no effect on offensive factors like acid and pepsin secretion.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Ratas
/
Femenino
/
Masculino
/
Liliaceae
/
Relación Dosis-Respuesta a Droga
/
Animales
/
Medicina Ayurvédica
/
Antiulcerosos
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
2002
Tipo del documento:
Artículo
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