Immunohistochemical demonstration of mycobacterial antigens in intracranial tuberculoma.
Indian J Exp Biol
;
1991 Jul; 29(7): 641-4
Artículo
en Inglés
| IMSEAR
| ID: sea-62444
ABSTRACT
Mycobacterial antigens have been demonstrated immunohistochemically in the paraffin sections of 10 intracranial tuberculous granulomas and the results were compared with the detection of acid fast bacilli by conventional Ziehl-Neelsen method. In none of the 10 specimens, acid fast bacilli were demonstrated while mycobacterial antigens were characterised as diffusely staining granular brownish-pink material within the cytoplasm of giant cells and macrophages. In 14 specimens of granulomatous lesions due to non-tuberculous aetiology, immunohistochemical stains were negative for mycobacterial antigen. Thus demonstration of mycobacterial antigen will be not only useful in establishing mycobacterial aetiology of a caseating intracranial granuloma but also can be used as an alternative method to the conventional Ziehl-Neelsen method.
Texto completo:
Disponible
Índice:
IMSEAR (Asia Sudoriental)
Asunto principal:
Coloración y Etiquetado
/
Tuberculoma
/
Encefalopatías
/
Humanos
/
Técnicas para Inmunoenzimas
/
Granuloma
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Mycobacterium tuberculosis
/
Antígenos Bacterianos
Idioma:
Inglés
Revista:
Indian J Exp Biol
Año:
1991
Tipo del documento:
Artículo
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