Antiparkinsonian activity and dopamine receptor binding studies of imidazolone derivatives.

Naithani, P K; Srivastava, V K; Saxena, A K; Barthwal, J P; Gupta, T K; Shanker, K

Naithani, P K; Srivastava, V K; Saxena, A K; Barthwal, J P; Gupta, T K; Shanker, K.

Indian J Exp Biol ; 1990 Dec; 28(12): 1145-8

Artículo en Inglés | IMSEAR | ID: sea-62901

ABSTRACT

ABSTRACT

Mannich bases and styryl derivatives of imidazolones were evaluated for their antiparkinsonian activity. Two compounds showed potent antiparkinsonian activity. These active compounds also showed binding with dopamine receptors in striatal membrane preparation of rat brain.

Asunto(s)

Animales; Antiparkinsonianos; Femenino; Imidazoles/química; Masculino; Estructura Molecular; Ratas; Receptores Dopaminérgicos/metabolismo

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Texto completo: Disponible Índice: IMSEAR (Asia Sudoriental) Asunto principal: Ratas / Femenino / Masculino / Estructura Molecular / Receptores Dopaminérgicos / Imidazoles / Animales / Antiparkinsonianos Idioma: Inglés Revista: Indian J Exp Biol Año: 1990 Tipo del documento: Artículo

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